Usage of "alkylators"

Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning.

alkylating agent

Termes relacionats

class of chemical compounds with similar applications or functions

Sinònims

Examples for "alkylating agent"

alkylating agent

Examples for "alkylating agent"

All had previously received at least one purine analogue or alkylating agent. 
 Pubmed 

The role of hyperthermia during regional alkylating agent chemotherapy is controversial. 
 Pubmed 

Standard therapy for MM has been an alkylating agent and corticosteroid. 
 Pubmed 

Thiotepa is an alkylating agent widely used in high-dose chemotherapy. 
 Pubmed 

Treatment with this alkylating agent chemically compromises alkyl-DNA repair functions. 
 Pubmed 

Ús de alkylators en anglès

HDAC inhibitors, DNA alkylators and nucleoside analogs are effective components of combination chemotherapy. 
 Pubmed 

On the other hand, the use of alkylators and topoisomerase II inhibitors is associated with an increased risk of t-AML. 
 Pubmed 

The protein level of MRP1 correlated with cellular resistance to busulfan and chlorambucil, and Rom exposure sensitized cells to these DNA alkylators. 
 Pubmed 

To determine a possible mechanism of their synergism, we analyzed the effects of HDAC inhibitors on the expression of drug transporters which export DNA alkylators. 
 Pubmed 

Alkylators a través del temps

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Significats de alkylators en anglès